Dr. David Greenhalgh to Lead Multi-Center Study to Improve Burn Outcomes

Burn Doctors at Shriners Hospitals for Children-Northern California

The Department of Defense awarded David Greenhalgh, M.D., a $2 million grant to fund a four-year study on how to improve outcomes in burn patients.

Dr. Greenhalgh is chief of burns at Shriners Hospitals for Children ─ Northern California and the University of California Davis Health System, where he leads a comprehensive and collaborative burn program that provides care for thousands of children and adults throughout California. The two regional medical facilities are located side-by-side in Sacramento in the heart of a growing medical community. Adults are treated at the UC Davis Medical Center, and children are treated at Shriners Hospital. Medical teams are engaged in collaborative research studies and provide resident and fellowship training for young doctors.

ABRUPT is the title of the multi-center study that will evaluate resuscitation practices for burn patients during the first 48 hours of hospitalization. Short for Acute Burn Resuscitation Observational Trial, ABRUPT will obtain descriptive information on burn resuscitation practices, specifically in the administration of albumin, a serum of proteins commonly found in blood plasma. The study will provide comparative data on the timing and dosage albumin.

“There has been debate for decades over what is the proper timing and dosage of albumin in patients with severe burn injuries,” says Dr. Greenhalgh. “ABRUPT will provide solid data to support ─ or dispute ─ the hypothesis that earlier administration of albumin results in an overall reduction in the amount of abnormal swelling in burn patients and, in turn, fewer respiratory complications.”

Twenty burn centers in the North America, including the UC Davis Medical Center, will participate in the study of 366 patients who:

  • are over 18 years old
  • sustained a burn injury of 20 percent total body surface area or more
  • are admitted to a burn center within 12 hours of injury.

Data will be collected through the Data Collection Center (DCC) of the American Burn Association at the University of California, Davis.  Dr. Greenhalgh is a past president of the American Burn Association.


Shriners Hospitals for Children is devoted to transforming the lives of children through excellence in treatment, teaching and research.  Located at 2425 Stockton Boulevard in Sacramento, Shriners Hospitals for Children – Northern California provides care to children with orthopaedic conditions, spinal cord injuries, burns, cleft lip, scars from any cause and other complex surgical needs. There are no barriers to care as admission is based on age and diagnosis.   Care is provided regardless of the family’s ability to pay. For further information call (916) 453-2000 or go online to www.shrinerschildrens.org.


Media Contact:  Catherine Curran | Public Relations (916) 453-2218 | ccurran@shrinenet.org


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